6/25/2023 0 Comments Hype pro 3 tumult![]() Because there are many more cancer specific proteins expressed inside cancer cells, the ability to target these with antibodies would open up a huge number of potential targets. Central to this challenge is that there are few known proteins that are expressed only on the surface of cancer cells and not on the surface of healthy cells. In our second poster, we presented an approach to addressing the second challenge of finding antibodies that are highly specific to cancer cells. This panel offers unmatched diversity of binding properties and binding locations, excellent developability and is highly differentiated from commonly used molecules. First, we have built what we believe to be by far the industry's largest collection of CD3 binders with more than 500 unique antibodies. Key results from this poster as are as follows. One of our posters that at ACR demonstrated data on our newly generated CD3 panel and its use in building optimized TCEs against to cancer targets EGFR and PSMA. Carl Hansen explained the following on the conference call in his prepared remarks: This catalog of antibodies, AbCellera claims, is by far the largest in the world of its kind and the breadth, speed and diversity of the panel may in fact be groundbreaking in the treatment of cancer.ĬEO Dr. These data show that the company, using its platform and with relative ease I may add, has been able to gather, catalog and analyze over 500 unique and potent bi-specific antibodies that appear to be comparable, or superior to clinical benchmarks. Under the surface however, the company continues to deliver on exactly what management has been telegraphing for some time now, fireworks to come from the pre-partnered programs effort, specifically, the T-cell engager programs.ĭuring the quarter, the company presented a trove of data highlighting the progress of the T-cell engager technology development effort it is currently pursuing. Not a stellar quarter for headlines in newsfeeds. The company only signed one new partnership, adding 3 new programs during the quarter, while the company reported that AbCellera partner, Teva Pharmaceutical ( TEVA), advanced a neurology molecule, discovered by AbCellera, into the clinic during the quarter, the company also reported no new program starts and the cash balance shrunk by over $90 million to $824 million. The first quarter, on the surface, appeared to be a rather boring and unproductive affair. In this article, I would like to dive into the quarter, specifically, the conference call around the TCE programs and explain my continued bullishness for the future. In the first quarter, AbCellera continued to deliver positive business momentum, only to be rewarded with further deep, on paper, shareholder losses. Creates an entirely self-contained directory that holds all the resources and JavaScript for your contentĬheck full list of features of Hype 4 Standard License here.Investing has a sadistic way of making you feel like you are the man in the above photo, with a massive pot of gold hiding somewhere in a vast labyrinth of wrong turns and dead ends.īeing a shareholder of AbCellera Biologics ( NASDAQ: ABCL ) over the last few years, I would argue, has been equally as frustrating however, I would also argue that the last few years have been nothing short of a tremendous success for the company itself from an "under the hood" business perspective.Outputs state of the art HTML5, CSS3 styles, & JavaScript.Supports all modern browsers & alerts about potential older cross-browser compatibility issues.Allows for content to be displayed on everything from desktops to iPhones & iPad.Cutting-edge effects: blur, image filters, backdrop filters, scale, skew, reflection, & 3D transforms.WebKit-based WYSYWIG “what you see is what you get” scene editing.Visually build action handlers to respond to taps, clicks, & animation events.Action handlers kick off & control timelines, transition between scenes, or run custom JavaScript.Create natural motion curves with bézier paths.Record mode watches your every move, automatically creating keyframes as needed.Easy to use keyframe-based animation system.From prototype to production, anyone can create rich interactive media with Hype. Tumult Hype outputs state-of-the-art HTML5, CSS3 styles, and JavaScript. HTML5 powers the modern web and allows for content to be displayed on everything from desktops to iPhones and iPads. Create animations that add a “wow” factor to web pages, infographics, presentations, digital magazines, ads, iBooks, educational content, app prototypes, portfolios, animated GIFs, videos, entire websites, and much more. Hype 4 is an award-winning HTML5 tool used by leading designers.
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